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  Indian J Med Microbiol
 

Figure 1: Serum testosterone levels in Wistar rats following 30-day oral administration of therapeutic dose equivalent levels (1.25, 2.50 and 5.00 mg/kg) of tramadol. Tramadol treated groups are sacrificed at the end of tramadol treatment, while reversible groups are allowed to recover for 30 days before sacrificed. Values are expressed as median (interquartile range) [median (IQR)]; n=5 animals per group. aP<0.05, bP<0.01: versus the control group. Data are analysed by using Kruskal-Wallis test and Dunn post test

Figure 1: Serum testosterone levels in Wistar rats following 30-day oral administration of therapeutic dose equivalent levels (1.25, 2.50 and 5.00 mg/kg) of tramadol. Tramadol treated groups are sacrificed at the end of tramadol treatment, while reversible groups are allowed to recover for 30 days before sacrificed. Values are expressed as median (interquartile range) [median (IQR)]; <i>n</i>=5 animals per group. <sup>a</sup><i>P</i><0.05, <sup>b</sup><i>P</i><0.01: <i>versus</i> the control group. Data are analysed by using Kruskal-Wallis test and Dunn post test