Close
  Indian J Med Microbiol
 

Figure 3: Electron micrograph of the ovary in rats. A: The normal control group shows nucleus of granulosa cells (N), zona pellucida (ZP), and lipid droplets (L), (3000×).B: The PCOS induction group shows nucleus (N) and disrupted cristae in mitochondria (M) in granulosa cell, (15000×).C: The clomiphene citrate group shows lipid (L) laden granulosa cells (GC) and thecal layer, vesicle (V) in zona pellucida (ZP), (15000×).D: The 400 mg/kg Pushyanuga churna group shows distinctive thecal layer (TL) and granulosal layer (GL). The inner layer of the granulosa cells shows presence of autophagosomes (arrow), (2000×).E: The 100 mg/kg novel herbal combination group shows distinctive thecal layer (TL), secretory cells (S) and lipid droplets (L). The cellular and nuclear morphology of cells in both these layers are normal, (2000×).F: The 200 mg/kg novel herbal combination group shows normal granulosa cells (GC) with lipid droplets (L), (3000×).G: The 200 mg/kg syrup formulation of novel herbal combination group shows active granulosa cell (GC) with nucleus (N) and electron dense secretory vesicles and normal thecal layer and electron dense secretory vesicles (arrows) and normal thecal layer, (6000×).

Figure 3: Electron micrograph of the ovary in rats. A: The normal control group shows nucleus of granulosa cells (N), zona pellucida (ZP), and lipid droplets (L), (3000×).B: The PCOS induction group shows nucleus (N) and disrupted cristae in mitochondria (M) in granulosa cell, (15000×).C: The clomiphene citrate group shows lipid (L) laden granulosa cells (GC) and thecal layer, vesicle (V) in zona pellucida (ZP), (15000×).D: The 400 mg/kg <i>Pushyanuga churna</i> group shows distinctive thecal layer (TL) and granulosal layer (GL). The inner layer of the granulosa cells shows presence of autophagosomes (arrow), (2000×).E: The 100 mg/kg novel herbal combination group shows distinctive thecal layer (TL), secretory cells (S) and lipid droplets (L). The cellular and nuclear morphology of cells in both these layers are normal, (2000×).F: The 200 mg/kg novel herbal combination group shows normal granulosa cells (GC) with lipid droplets (L), (3000×).G: The 200 mg/kg syrup formulation of novel herbal combination group shows active granulosa cell (GC) with nucleus (N) and electron dense secretory vesicles and normal thecal layer and electron dense secretory vesicles (arrows) and normal thecal layer, (6000×).